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Heart health: Supplements don't work, with one exception- Ana Sandoiu

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A new review finds that the most widely used supplements do not protect the heart against cardiovascular disease. However, folic acid may prevent stroke.
Most supplements do not keep your heart healthy, suggests a new review. The National Institutes of Health (NIH) estimate that one-third of the entire population of the United States are taking some form of supplement Supplements are meant to raise our nutritional intake when food alone is not enough to provide the daily recommended dose. However, some claim that supplements may prevent chronic diseases such as cancer or cardiovascular disease. Vitamins A, E, and C, for example, have been suggested to keep cancer at bay, while some studies have proposed that folic acid, vitamin E, and vitamin D might be helpful for preventing cardiovascular disease. However, the scientific evidence available is conflicting. The official message that government authorities and nonprofit organizations have been putting forth to the public is that, even t…
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Radiation-Induced CAD: Incidence, Diagnosis, and Management Outcomes- Nyal Borges; Samir R. Kapadia

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Mediastinal radiation therapy is a commonly used treatment modality for malignancies involving the thorax. First described in the mid-1960s, radiation-induced heart disease is an under-recognized phenomenon associated with considerable morbidity and mortality. Radiation-induced heart disease can manifest as the pathology of the epicardial and endocardial coronary vessels resulting in coronary obstruction, semilunar and atrioventricular valves resulting in stenosis or regurgitation due to valvular fibrosis, myocardium with resultant cardiomyopathy, and conduction system and pericardium with pericardial constriction and inflammation. In this review, we will discuss radiation-induced coronary artery disease (CAD), focusing primarily on incidence, diagnosis, and management.
Historically, Hodgkin's lymphoma and breast cancer treatments have included thoracic radiation therapy, resulting in exposure of cardiac tissues to radiation. Most of our understanding of radiation effects on card…
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Targeting 'microtubules' could prevent heart failure-Rachel Sokol

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Researchers publish a study in the journal Nature Medicine that determined the cause of "stiff heart." The findings could help to prevent future cases of heart failure. Microtubules (depicted here) may be key to the future treatment of heart failure. One of the most common causes of congestive heart failure is "stiff heart syndrome." According to Dr. Jerry Sokol — a cardiologist in Deer Park, NY — this causes fluid to build up and back up into the lungs. This occurs "usually in patients older than age 60," he says. At the microcellular level, they revealed that stiff heart appears to be related to microtubules in the cells of the heart muscle. By treating these microtubules with newly developed research and medications, cardiac surgeons will soon be able to more effectively treat patients with this type of congestive heart failure. The new study was led by Dr. Ben Prosser — an assistant professor of physiology in the Perelman School of Medicine at the Univ…
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